diff --git a/EvoScientist/config/settings.py b/EvoScientist/config/settings.py
index d204968..01c5b3e 100644
--- a/EvoScientist/config/settings.py
+++ b/EvoScientist/config/settings.py
@@ -60,6 +60,7 @@ class EvoScientistConfig:
 
     # API Keys
     anthropic_api_key: str = ""
+    anthropic_base_url: str = ""
     openai_api_key: str = ""
     nvidia_api_key: str = ""
     google_api_key: str = ""
@@ -329,6 +330,7 @@ def list_config() -> dict[str, Any]:
 # Environment variable mappings
 _ENV_MAPPINGS = {
     "anthropic_api_key": "ANTHROPIC_API_KEY",
+    "anthropic_base_url": "ANTHROPIC_BASE_URL",
     "openai_api_key": "OPENAI_API_KEY",
     "nvidia_api_key": "NVIDIA_API_KEY",
     "google_api_key": "GOOGLE_API_KEY",
@@ -398,6 +400,8 @@ def apply_config_to_env(config: EvoScientistConfig) -> None:
     """
     if config.anthropic_api_key and not os.environ.get("ANTHROPIC_API_KEY"):
         os.environ["ANTHROPIC_API_KEY"] = config.anthropic_api_key
+    if config.anthropic_base_url and not os.environ.get("ANTHROPIC_BASE_URL"):
+        os.environ["ANTHROPIC_BASE_URL"] = config.anthropic_base_url
     if config.openai_api_key and not os.environ.get("OPENAI_API_KEY"):
         os.environ["OPENAI_API_KEY"] = config.openai_api_key
     if config.nvidia_api_key and not os.environ.get("NVIDIA_API_KEY"):
diff --git a/EvoScientist/llm/models.py b/EvoScientist/llm/models.py
index 56ab2fc..3a03a85 100644
--- a/EvoScientist/llm/models.py
+++ b/EvoScientist/llm/models.py
@@ -196,9 +196,18 @@ def get_chat_model(
             else:
                 provider = "anthropic"  # Default fallback
 
-    # Third-party providers → route through OpenAI provider with base_url
+    # Anthropic base_url override (e.g. ccproxy at localhost:8000/api/v1)
     _is_third_party = provider in _THIRD_PARTY_PROVIDERS
-    if provider in _THIRD_PARTY_PROVIDERS:
+    if provider == "anthropic":
+        base_url = os.environ.get("ANTHROPIC_BASE_URL", "")
+        if base_url:
+            kwargs["base_url"] = base_url
+        api_key = os.environ.get("ANTHROPIC_API_KEY", "")
+        if api_key:
+            kwargs["api_key"] = api_key
+
+    # Third-party providers → route through OpenAI provider with base_url
+    elif provider in _THIRD_PARTY_PROVIDERS:
         base_url_default, api_key_env = _THIRD_PARTY_PROVIDERS[provider]
         if provider == "custom":
             base_url = os.environ.get("CUSTOM_BASE_URL", "")
diff --git a/tests/test_llm.py b/tests/test_llm.py
index f4800b0..fe5ec87 100644
--- a/tests/test_llm.py
+++ b/tests/test_llm.py
@@ -392,6 +392,35 @@ class TestThirdPartyRouting:
         assert call_kwargs["base_url"] == "https://my-llm.example.com/v1"
         assert call_kwargs["api_key"] == "custom-key-789"
 
+    @patch("EvoScientist.llm.models.init_chat_model")
+    def test_anthropic_base_url_override(self, mock_init, monkeypatch):
+        """Anthropic provider should support base_url override (e.g. ccproxy)."""
+        mock_init.return_value = "mock_model"
+        monkeypatch.setenv("ANTHROPIC_BASE_URL", "http://localhost:8000/api/v1")
+        monkeypatch.setenv("ANTHROPIC_API_KEY", "sk-dummy")
+
+        get_chat_model("claude-sonnet-4-6", provider="anthropic")
+
+        call_kwargs = mock_init.call_args[1]
+        assert call_kwargs["model_provider"] == "anthropic"
+        assert call_kwargs["base_url"] == "http://localhost:8000/api/v1"
+        assert call_kwargs["api_key"] == "sk-dummy"
+        # Should still get anthropic auto-config (thinking)
+        assert "thinking" in call_kwargs
+
+    @patch("EvoScientist.llm.models.init_chat_model")
+    def test_anthropic_no_base_url_when_unset(self, mock_init, monkeypatch):
+        """Anthropic provider should not set base_url when env var is empty."""
+        mock_init.return_value = "mock_model"
+        monkeypatch.delenv("ANTHROPIC_BASE_URL", raising=False)
+        monkeypatch.setenv("ANTHROPIC_API_KEY", "sk-real")
+
+        get_chat_model("claude-sonnet-4-6", provider="anthropic")
+
+        call_kwargs = mock_init.call_args[1]
+        assert call_kwargs["model_provider"] == "anthropic"
+        assert "base_url" not in call_kwargs
+
     @patch("EvoScientist.llm.models.init_chat_model")
     def test_third_party_no_reasoning(self, mock_init, monkeypatch):
         """Third-party providers routed through OpenAI should NOT get auto-reasoning."""